This study was descriptive by means of quantitative framework employing a cross-sectional method. Data of respondents’ knowledge was gathered through questionnaires, while data of nurses’ interpersonal communication, technical skill, and the application of nursing process were obtained from observations. The number of research subjects involved in this study was all 50 nurse practitioners who had been giving upbringing treatment and assigned in hospitalizing and emergency installations, who met the criteria of: having minimum education of SPK, had been employed in the hospital at a minimum of a year, not on leave nor assigned for higher education, available becoming respondent. Hypothesis test was using Spearman Rank correlation at a significance level of 95% or

The calculation resulted in the correlation of knowledge to the application of nursing process at rho = 0.186 and p = 0.197; the correlation of interpersonal communication to the application of nursing process at rho = 0.384 and p = 0.006; and the correlation of technical skill to the application of nursing process at rho = 0.343 and p = 0.015.

This study showed that there was no significant correlation of knowledge to the application of nursing process; there was a positive and significant correlation of interpersonal communication to the application of nursing process; and there was a positive and significant correlation of technical skill to the application of nursing process.